| Date | Location | Result | |
| Jun 12, 2021 | Nashville, Tenn. | Vanderbilt 4, East Carolina 1 | Box score |
| Jun 11, 2021 | Nashville, Tenn. | Vanderbilt 2, East Carolina 0 | Box score |
| Jun 06, 2021 | Greenville, N.C. | East Carolina 9, Maryland 6 | Box score |
| Jun 05, 2021 | Greenville, N.C. | East Carolina 7, Charlotte 5 | Box score |
| Jun 04, 2021 | Greenville, N.C. | East Carolina 8, Norfolk State 5 | Box score |
| May 29, 2021 | Clearwater, Fla. | UCF 2, East Carolina 1 | Box score |
| May 29, 2021 | Clearwater, Fla. | East Carolina 5, UCF 2 | Box score |
| May 28, 2021 | Clearwater, Fla. | East Carolina 12, Memphis 0 | Box score |
| May 26, 2021 | Clearwater, Fla. | East Carolina 13, Cincinnati 9 | Box score |
| May 25, 2021 | Clearwater, Fla. | Memphis 11, East Carolina 1 | Box score |
| May 22, 2021 | Tampa, Fla. | USF 8, East Carolina 2 | Box score |
| May 21, 2021 | Tampa, Fla. | USF 7, East Carolina 0 | Box score |
| May 20, 2021 | Tampa, Fla. | East Carolina 5, USF 2 | Box score |
| May 20, 2021 | Tampa, Fla. | East Carolina 10, USF 1 | Box score |
| May 16, 2021 | Cincinnati, OH | East Carolina 5, Cincinnati 2 | Box score |
| May 15, 2021 | Cincinnati, OH | East Carolina 7, Cincinnati 6 | Box score |
| May 14, 2021 | Cincinnati, OH | Cincinnati 7, East Carolina 6 | Box score |
| May 14, 2021 | Cincinnati, OH | East Carolina 8, Cincinnati 4 | Box score |
| May 09, 2021 | Greenville, N.C. | East Carolina 9, Tulane 1 | Box score |
| May 08, 2021 | Greenville, N.C. | Tulane 7, East Carolina 6 | Box score |
| May 08, 2021 | Greenville, N.C. | East Carolina 7, Tulane 4 | Box score |
| May 07, 2021 | Greenville, N.C. | East Carolina 12, Tulane 4 | Box score |
| May 02, 2021 | Wichita, Kan. | Wichita State 11, East Carolina 9 | Box score |
| May 01, 2021 | Wichita, Kan. | East Carolina 11, Wichita State 3 | Box score |
| Apr 30, 2021 | Wichita, Kan. | Wichita State 12, East Carolina 2 | Box score |
| Apr 30, 2021 | Wichita, Kan. | East Carolina 10, Wichita State 0 | Box score |
| Apr 25, 2021 | Greenville, N.C. | UCF 6, East Carolina 1 | Box score |
| Apr 24, 2021 | Greenville, N.C. | East Carolina 11, UCF 8 | Box score |
| Apr 23, 2021 | Greenville, N.C. | UCF 10, East Carolina 5 | Box score |
| Apr 23, 2021 | Greenville, N.C. | East Carolina 4, UCF 2 | Box score |
| Apr 11, 2021 | Greenville, N.C. | East Carolina 7, Memphis 1 | Box score |
| Apr 10, 2021 | Greenville, N.C. | East Carolina 8, Memphis 7 | Box score |
| Apr 09, 2021 | Greenville, N.C. | East Carolina 5, Memphis 3 | Box score |
| Apr 09, 2021 | Greenville, N.C. | East Carolina 12, Memphis 2 | Box score |
| Apr 03, 2021 | Greenville, N.C. | East Carolina 2, Cincinnati 0 | Box score |
| Apr 03, 2021 | Greenville, N.C. | East Carolina 13, Cincinnati 3 | Box score |
| Apr 02, 2021 | Greenville, N.C. | East Carolina 7, Cincinnati 0 | Box score |
| Apr 01, 2021 | Greenville, NC | East Carolina 5, Cincinnati 4 | Box score |
| Mar 30, 2021 | Greenville, N.C. | East Carolina 11, North Carolina 10 | Box score |
| Mar 27, 2021 | Elon, N.C. | Elon 2, East Carolina 1 | Box score |
| Mar 26, 2021 | Elon, N.C. | East Carolina 15, Elon 0 | Box score |
| Mar 23, 2021 | Chapel Hill, N.C. | North Carolina 8, East Carolina 1 | Box score |
| Mar 21, 2021 | Greenville, N.C. | East Carolina 11, Illinois State 8 | Box score |
| Mar 20, 2021 | Greenville, N.C. | East Carolina 11, Illinois State 5 | Box score |
| Mar 19, 2021 | Greenville, N.C. | East Carolina 4, Illinois State 3 | Box score |
| Mar 17, 2021 | Wilmington, N.C. | UNCW 10, East Carolina 2 | Box score |
| Mar 14, 2021 | Greenville, N.C. | East Carolina 3, Charlotte 1 | Box score |
| Mar 13, 2021 | Greenville, N.C. | East Carolina 3, Charlotte 1 | Box score |
| Mar 12, 2021 | Greenville, N.C. | East Carolina 7, Charlotte 4 | Box score |
| Mar 09, 2021 | Durham, N.C. | East Carolina 11, Duke 5 | Box score |
| Mar 07, 2021 | Greenville, N.C. | East Carolina 10, Appalachian State 2 | Box score |
| Mar 06, 2021 | Greenville, N.C. | East Carolina 5, Appalachian State 2 | Box score |
| Mar 05, 2021 | Greenville, N.C. | East Carolina 13, Appalachian State 2 | Box score |
| Mar 03, 2021 | Greenville, N.C. | Old Dominion 6, East Carolina 5 | Box score |
| Feb 28, 2021 | Statesboro, Ga. | East Carolina 9, Georgia Southern 2 | Box score |
| Feb 27, 2021 | Statesboro, Ga. | Georgia Southern 10, East Carolina 7 | Box score |
| Feb 26, 2021 | Statesboro, Ga. | East Carolina 6, Georgia Southern 4 | Box score |
| Feb 23, 2021 | Greenville, N.C. | East Carolina 6, Duke 1 | Box score |
| Feb 21, 2021 | Greenville, N.C. | East Carolina 12, Rhode Island 4 | Box score |
| Feb 20, 2021 | Greenville, N.C. | East Carolina 7, Rhode Island 1 | Box score |
| Feb 19, 2021 | Greenville, N.C. | East Carolina 3, Rhode Island 2 | Box score |