| Date | Location | Result | |
| Nov 26, 2005 | Greenville, N.C. | East Carolina 31, UAB 23 | Box score |
| Nov 19, 2005 | Huntington, W.Va. | East Carolina 34, Marshall 29 | Box score |
| Nov 12, 2005 | Tulsa, Okla. | Tulsa 45, East Carolina 13 | Box score |
| Oct 29, 2005 | Greenville, N.C. | UCF 30, East Carolina 20 | Box score |
| Oct 22, 2005 | Memphis, Tenn. | Memphis 27, East Carolina 24 | Box score |
| Oct 15, 2005 | Dallas, Texas | East Carolina 24, SMU 17 | Box score |
| Oct 08, 2005 | Greenville, NC | East Carolina 41, Rice 28 | Box score |
| Oct 01, 2005 | Greenville, N.C. | Southern Miss 33, East Carolina 7 | Box score |
| Sep 24, 2005 | Morgantown, W.Va. | West Virginia 20, East Carolina 15 | Box score |
| Sep 17, 2005 | Winston-Salem, N.C. | Wake Forest 44, East Carolina 34 | Box score |
| Sep 03, 2005 | Greenville, N.C. | East Carolina 24, Duke 21 | Box score |