| Date | Location | Result | |
| 3/8/06 | Memphis, Tenn. (FedExForum) | UCF 65, East Carolina 52 | Box score |
| 3/4/06 | HATTIESBURG, Miss. (Reed Green Coliseum) | Southern Miss 74, East Carolina 56 | Box score |
| 02/25/06 | Greenville, N.C. | Tulane 66, East Carolina 53 | Box score |
| 2/22/06 | Orlando, Fla. | UCF 69, East Carolina 49 | Box score |
| 02/18/06 | Greenville, N.C. | East Carolina 63, Marshall 59 | Box score |
| 2/15/06 | Autry Court, Houston | Rice 62, East Carolina 54 | Box score |
| 02/11/06 | Birmingham, Ala. (Bartow Arena) | UAB 72, East Carolina 64 | Box score |
| 02/04/06 | Greenville, N.C. | Houston 64, East Carolina 60 | Box score |
| 02/01/06 | Huntington, W.Va.; Cam Henderson Center | Marshall 72, East Carolina 66 | Box score |
| 01/28/06 | Greenville, N.C. | East Carolina 59, Tulsa 45 | Box score |
| 01/25/06 | Greenville, N.C. | UCF 91, East Carolina 88 | Box score |
| 01/21/06 | New Orleans, La. (Fogelman Arena) | Tulane 60, East Carolina 52 | Box score |
| 01/18/06 | Greenville, N.C. | SMU 74, East Carolina 70 | Box score |
| 01/14/06 | El Paso, Texas - Don Haskins Center | UTEP 58, East Carolina 45 | Box score |
| 01/11/06 | Greenville, N.C. | Memphis 77, East Carolina 67 | Box score |
| 01/07/06 | Greenville, N.C. | East Carolina 80, Saint Paul's 74 | Box score |
| 01/03/06 | Winston-Salem, N.C. (Joel Coliseum) | Wake Forest 58, East Carolina 54 | Box score |
| 12/31/05 | Greenville, N.C. | East Carolina 82, UNC Wilmington 69 | Box score |
| 12/28/05 | Greenville, N.C. | East Carolina 87, Limestone 54 | Box score |
| 12/21/05 | Savage Hall (Toledo, OH) | Toledo 73, East Carolina 62 | Box score |
| 12/18/05 | Winthrop Coliseum--Rock Hill, SC | Winthrop 70, East Carolina 48 | Box score |
| 12/10/05 | Greenville, N.C. | Western Carolina 56, East Carolina 48 | Box score |
| 12/06/05 | Greenville, N.C. | UNC Greensboro 78, East Carolina 70 | Box score |
| 12/03/05 | Norfolk, VA/Constant Convocation Center | Old Dominion 79, East Carolina University 53 | Box score |
| 11/30/05 | Benjamin Johnson Arena, Spartanburg, SC | ECU 66, Wofford 62 | Box score |
| 11/26/05 | Greenville, N.C. | East Carolina 70, Wofford 68 | Box score |
| 11/22/05 | Greenville, N.C. | Gardner-Webb 77, East Carolina 72 | Box score |
| 11/18/05 | Greenville, N.C. | East Carolina 86, North Carolina A&T 75 | Box score |